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Shiga toxin suppresses noncanonical inflammasome responses to cytosolic LPS

Inflammatory caspase-dependent cytosolic LPS sensing is a critical arm of host defense against bacteria. How pathogens overcome this pathway to establish infections is largely unknown. Enterohemorrhagic Escherichia coli (EHEC) is a clinically significant human pathogen causing hemorrhagic colitis an...

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Bibliografische gegevens
Gepubliceerd in:Sci Immunol
Hoofdauteurs: Havira, Morena S, Ta, Atri, Kumari, Puja, Wang, Chengliang, Russo, Ashley J, Ruan, Jianbin, Rathinam, Vijay A, Vanaja, Sivapriya Kailasan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7717664/
https://ncbi.nlm.nih.gov/pubmed/33246946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.abc0217
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