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Piperine ameliorates SCA17 neuropathology by reducing ER stress
BACKGROUND: Spinocerebellar ataxia 17 (SCA17) belongs to the family of neurodegenerative diseases caused by polyglutamine (polyQ) expansion. In SCA17, polyQ expansion occurs in the TATA box binding protein (TBP) and leads to the misfolding of TBP and the preferential degeneration in the cerebellar P...
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| 出版年: | Mol Neurodegener |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5789626/ https://ncbi.nlm.nih.gov/pubmed/29378605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-018-0236-x |
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