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Molecular Mechanisms and Therapeutics for SCA17

Spinocerebellar ataxia type 17 (SCA17) is caused by polyglutamine (polyQ) expansion in the TATA box-binding protein (TBP), which functions as a general transcription factor. Like other polyQ expansion-mediated diseases, SCA17 is characterized by late-onset and selective neurodegeneration, despite th...

詳細記述

保存先:
書誌詳細
出版年:Neurotherapeutics
主要な著者: Liu, Qiong, Pan, Yongcheng, Li, Xiao-Jiang, Li, Shihua
フォーマット: Artigo
言語:Inglês
出版事項: Springer International Publishing 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985407/
https://ncbi.nlm.nih.gov/pubmed/31317427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-019-00762-z
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