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Molecular Mechanisms and Therapeutics for SCA17
Spinocerebellar ataxia type 17 (SCA17) is caused by polyglutamine (polyQ) expansion in the TATA box-binding protein (TBP), which functions as a general transcription factor. Like other polyQ expansion-mediated diseases, SCA17 is characterized by late-onset and selective neurodegeneration, despite th...
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| Publicado no: | Neurotherapeutics |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6985407/ https://ncbi.nlm.nih.gov/pubmed/31317427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-019-00762-z |
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