Piperine ameliorates SCA17 neuropathology by reducing ER stress

BACKGROUND: Spinocerebellar ataxia 17 (SCA17) belongs to the family of neurodegenerative diseases caused by polyglutamine (polyQ) expansion. In SCA17, polyQ expansion occurs in the TATA box binding protein (TBP) and leads to the misfolding of TBP and the preferential degeneration in the cerebellar P...

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Bibliografiske detaljer
Udgivet i:Mol Neurodegener
Main Authors: Guo, Jifeng, Cui, Yiting, Liu, Qiong, Yang, Yang, Li, Yujing, Weng, Ling, Tang, Beisha, Jin, Peng, Li, Xiao-Jiang, Yang, Su, Li, Shihua
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789626/
https://ncbi.nlm.nih.gov/pubmed/29378605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-018-0236-x
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