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Piperine ameliorates SCA17 neuropathology by reducing ER stress
BACKGROUND: Spinocerebellar ataxia 17 (SCA17) belongs to the family of neurodegenerative diseases caused by polyglutamine (polyQ) expansion. In SCA17, polyQ expansion occurs in the TATA box binding protein (TBP) and leads to the misfolding of TBP and the preferential degeneration in the cerebellar P...
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| Опубликовано в: : | Mol Neurodegener |
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| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5789626/ https://ncbi.nlm.nih.gov/pubmed/29378605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-018-0236-x |
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