Piperine ameliorates SCA17 neuropathology by reducing ER stress

BACKGROUND: Spinocerebellar ataxia 17 (SCA17) belongs to the family of neurodegenerative diseases caused by polyglutamine (polyQ) expansion. In SCA17, polyQ expansion occurs in the TATA box binding protein (TBP) and leads to the misfolding of TBP and the preferential degeneration in the cerebellar P...

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Библиографические подробности
Опубликовано в: :Mol Neurodegener
Главные авторы: Guo, Jifeng, Cui, Yiting, Liu, Qiong, Yang, Yang, Li, Yujing, Weng, Ling, Tang, Beisha, Jin, Peng, Li, Xiao-Jiang, Yang, Su, Li, Shihua
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2018
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789626/
https://ncbi.nlm.nih.gov/pubmed/29378605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-018-0236-x
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