Cerebellum-enriched protein INPP5A contributes to selective neuropathology in mouse model of spinocerebellar ataxias type 17

Spinocerebellar ataxias 17 (SCA17) is caused by polyglutamine (polyQ) expansion in the TATA box-binding protein (TBP). The selective neurodegeneration in the cerebellum in SCA17 raises the question of why ubiquitously expressed polyQ proteins can cause neurodegeneration in distinct brain regions in...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Liu, Qiong, Huang, Shanshan, Yin, Peng, Yang, Su, Zhang, Jennifer, Jing, Liang, Cheng, Siying, Tang, Beisha, Li, Xiao-Jiang, Pan, Yongcheng, Li, Shihua
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7046734/
https://ncbi.nlm.nih.gov/pubmed/32107387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14931-8
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items