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Large Polyglutamine Repeats Cause Muscle Degeneration in SCA17 Mice
In polyglutamine (polyQ) diseases, large polyQ repeats cause juvenile cases with different symptoms than adult-onset patients, who carry smaller expanded polyQ repeats. The mechanisms behind the differential pathology mediated by different polyQ repeat lengths remain unknown. By studying knock-in mo...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4598297/ https://ncbi.nlm.nih.gov/pubmed/26387956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.08.060 |
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