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DNA methylation alterations in iPSC- and hESC-derived neurons: potential implications for neurological disease modeling
BACKGROUND: Genetic predisposition and epigenetic alterations are both considered to contribute to sporadic neurodegenerative diseases (NDDs) such as Parkinson’s disease (PD). Since cell reprogramming and the generation of induced pluripotent stem cells (iPSCs) are themselves associated with major e...
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| Wydane w: | Clin Epigenetics |
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| Główni autorzy: | , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BioMed Central
2018
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5789607/ https://ncbi.nlm.nih.gov/pubmed/29422978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0440-0 |
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