DNA methylation alterations in iPSC- and hESC-derived neurons: potential implications for neurological disease modeling

BACKGROUND: Genetic predisposition and epigenetic alterations are both considered to contribute to sporadic neurodegenerative diseases (NDDs) such as Parkinson’s disease (PD). Since cell reprogramming and the generation of induced pluripotent stem cells (iPSCs) are themselves associated with major e...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Clin Epigenetics
Hlavní autoři: de Boni, Laura, Gasparoni, Gilles, Haubenreich, Carolin, Tierling, Sascha, Schmitt, Ina, Peitz, Michael, Koch, Philipp, Walter, Jörn, Wüllner, Ullrich, Brüstle, Oliver
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789607/
https://ncbi.nlm.nih.gov/pubmed/29422978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0440-0
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky