Improved cell therapy protocol for Parkinson’s disease based on differentiation efficiency and safety of hESC-, hiPSC and non-human primate iPSC-derived DA neurons

The main motor symptoms of Parkinson’s disease are due to the loss of dopaminergic (DA) neurons in the ventral midbrain (VM). For the future treatment of Parkinson’s disease with cell transplantation it is important to develop efficient differentiation methods for production of human iPSCs and hESCs...

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Bibliografiske detaljer
Main Authors: Maria, Sundberg, Helle, Bogetofte, Tristan, Lawson, Gaynor, Smith, Arnar, Astradsson, Michele, Moore, Teresia, Osborn, Oliver, Cooper, Roger, Spealman, Penelope, Hallett, Ole, Isacson
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775937/
https://ncbi.nlm.nih.gov/pubmed/23666606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1415
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