Successful function of autologous iPSC-derived dopamine neurons following transplantation in a non-human primate model of Parkinson's disease

Autologous transplantation of patient-specific iPSC-derived neurons is a potential clinical approach for treatment of neurological disease. Preclinical demonstration of long-term efficacy, feasibility and safety of iPSC-derived dopamine neurons in non human primate models will be an important step i...

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Udgivet i:Cell Stem Cell
Main Authors: Hallett, Penelope J, Deleidi, Michela, Astradsson, Arnar, Smith, Gaynor A., Cooper, Oliver, Osborn, Teresia, Sundberg, Maria, Moore, Michele A., Perez-Torres, Eduardo, Brownell, Anna-Liisa, Schumacher, James, Spealman, Roger D., Isacson, Ole
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462124/
https://ncbi.nlm.nih.gov/pubmed/25732245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.01.018
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