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Development of histocompatible primate induced pluripotent stem cells for neural transplantation

Immune rejection and risk of tumor formation are perhaps the greatest hurdles in the field of stem cell transplantation. Here, we report the generation of several lines of induced pluripotent stem cells (iPSCs) from Cynomolgus macaque (CM) skin fibroblasts carrying specific major histocompatibility...

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Detalhes bibliográficos
Main Authors: Deleidi, Michela, Hargus, Gunnar, Hallett, Penelope, Osborn, Teresia, Isacson, Ole
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340906/
https://ncbi.nlm.nih.gov/pubmed/21608081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.662
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