Oct4-Induced Reprogramming Is Required for Adult Brain Neural Stem Cell Differentiation into Midbrain Dopaminergic Neurons

Neural stem cells (NSCs) lose their competency to generate region-specific neuronal populations at an early stage during embryonic brain development. Here we investigated whether epigenetic modifications can reverse the regional restriction of mouse adult brain subventricular zone (SVZ) NSCs. Using...

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書誌詳細
主要な著者: Deleidi, Michela, Cooper, Oliver, Hargus, Gunnar, Levy, Adam, Isacson, Ole
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2011
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104995/
https://ncbi.nlm.nih.gov/pubmed/21655272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019926
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