Direct Reprogramming of Human Fetal- and Stem Cell-Derived Glial Progenitor Cells into Midbrain Dopaminergic Neurons

Human glial progenitor cells (hGPCs) are promising cellular substrates to explore for the in situ production of new neurons for brain repair. Proof of concept for direct neuronal reprogramming of glial progenitors has been obtained in mouse models in vivo, but conversion using human cells has not ye...

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Publicat a:Stem Cell Reports
Autors principals: Nolbrant, Sara, Giacomoni, Jessica, Hoban, Deirdre B., Bruzelius, Andreas, Birtele, Marcella, Chandler-Militello, Devin, Pereira, Maria, Ottosson, Daniella Rylander, Goldman, Steven A., Parmar, Malin
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7562948/
https://ncbi.nlm.nih.gov/pubmed/32976765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.08.013
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