Direct Reprogramming of Human Fetal- and Stem Cell-Derived Glial Progenitor Cells into Midbrain Dopaminergic Neurons

Human glial progenitor cells (hGPCs) are promising cellular substrates to explore for the in situ production of new neurons for brain repair. Proof of concept for direct neuronal reprogramming of glial progenitors has been obtained in mouse models in vivo, but conversion using human cells has not ye...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Nolbrant, Sara, Giacomoni, Jessica, Hoban, Deirdre B., Bruzelius, Andreas, Birtele, Marcella, Chandler-Militello, Devin, Pereira, Maria, Ottosson, Daniella Rylander, Goldman, Steven A., Parmar, Malin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7562948/
https://ncbi.nlm.nih.gov/pubmed/32976765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.08.013
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