Direct Reprogramming of Human Fetal- and Stem Cell-Derived Glial Progenitor Cells into Midbrain Dopaminergic Neurons

Human glial progenitor cells (hGPCs) are promising cellular substrates to explore for the in situ production of new neurons for brain repair. Proof of concept for direct neuronal reprogramming of glial progenitors has been obtained in mouse models in vivo, but conversion using human cells has not ye...

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Gepubliceerd in:Stem Cell Reports
Hoofdauteurs: Nolbrant, Sara, Giacomoni, Jessica, Hoban, Deirdre B., Bruzelius, Andreas, Birtele, Marcella, Chandler-Militello, Devin, Pereira, Maria, Ottosson, Daniella Rylander, Goldman, Steven A., Parmar, Malin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7562948/
https://ncbi.nlm.nih.gov/pubmed/32976765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.08.013
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