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Improved cell therapy protocol for Parkinson’s disease based on differentiation efficiency and safety of hESC-, hiPSC and non-human primate iPSC-derived DA neurons

The main motor symptoms of Parkinson’s disease are due to the loss of dopaminergic (DA) neurons in the ventral midbrain (VM). For the future treatment of Parkinson’s disease with cell transplantation it is important to develop efficient differentiation methods for production of human iPSCs and hESCs...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Maria, Sundberg, Helle, Bogetofte, Tristan, Lawson, Gaynor, Smith, Arnar, Astradsson, Michele, Moore, Teresia, Osborn, Oliver, Cooper, Roger, Spealman, Penelope, Hallett, Ole, Isacson
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775937/
https://ncbi.nlm.nih.gov/pubmed/23666606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1415
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