DNA methylation alterations in iPSC- and hESC-derived neurons: potential implications for neurological disease modeling

BACKGROUND: Genetic predisposition and epigenetic alterations are both considered to contribute to sporadic neurodegenerative diseases (NDDs) such as Parkinson’s disease (PD). Since cell reprogramming and the generation of induced pluripotent stem cells (iPSCs) are themselves associated with major e...

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Dades bibliogràfiques
Publicat a:Clin Epigenetics
Autors principals: de Boni, Laura, Gasparoni, Gilles, Haubenreich, Carolin, Tierling, Sascha, Schmitt, Ina, Peitz, Michael, Koch, Philipp, Walter, Jörn, Wüllner, Ullrich, Brüstle, Oliver
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789607/
https://ncbi.nlm.nih.gov/pubmed/29422978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0440-0
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