Communication between N terminus and loop2 tunes Orai activation

Ca(2+) release-activated Ca(2+) (CRAC) channels constitute the major Ca(2+) entry pathway into the cell. They are fully reconstituted via intermembrane coupling of the Ca(2+)-selective Orai channel and the Ca(2+)-sensing protein STIM1. In addition to the Orai C terminus, the main coupling site for S...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Fahrner, Marc, Pandey, Saurabh K., Muik, Martin, Traxler, Lukas, Butorac, Carmen, Stadlbauer, Michael, Zayats, Vasilina, Krizova, Adéla, Plenk, Peter, Frischauf, Irene, Schindl, Rainer, Gruber, Hermann J., Hinterdorfer, Peter, Ettrich, Rüdiger, Romanin, Christoph, Derler, Isabella
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2018
Предметы:
Signal Transduction
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787804/
https://ncbi.nlm.nih.gov/pubmed/29237733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.812693
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