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Authentic CRAC channel activity requires STIM1 and the conserved portion of the Orai N terminus
Calcium (Ca(2+)) is an essential second messenger required for diverse signaling processes in immune cells. Ca(2+) release-activated Ca(2+) (CRAC) channels represent one main Ca(2+) entry pathway into the cell. They are fully reconstituted via two proteins, the stromal interaction molecule 1 (STIM1)...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5787803/ https://ncbi.nlm.nih.gov/pubmed/29237734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.812206 |
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