Molecular Determinants within N Terminus of Orai3 Protein That Control Channel Activation and Gating

STIM1 and Orai represent the key components of Ca(2+) release-activated Ca(2+) channels. Activation of Orai channels requires coupling of the C terminus of STIM1 to the N and C termini of Orai. Although the latter appears to be central in the interaction with STIM1, the role of the N terminus and pa...

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Main Authors: Bergsmann, Judith, Derler, Isabella, Muik, Martin, Frischauf, Irene, Fahrner, Marc, Pollheimer, Philipp, Schwarzinger, Clemens, Gruber, Hermann J., Groschner, Klaus, Romanin, Christoph
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173129/
https://ncbi.nlm.nih.gov/pubmed/21724845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.227546
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