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A Ca(2+) Release-activated Ca(2+) (CRAC) Modulatory Domain (CMD) within STIM1 Mediates Fast Ca(2+)-dependent Inactivation of ORAI1 Channels
STIM1 and ORAI1, the two limiting components in the Ca(2+) release-activated Ca(2+) (CRAC) signaling cascade, have been reported to interact upon store depletion, culminating in CRAC current activation. We have recently identified a modulatory domain between amino acids 474 and 485 in the cytosolic...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2757196/ https://ncbi.nlm.nih.gov/pubmed/19622747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C109.024083 |
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