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Plasticity in Ca(2+) selectivity of Orai1/Orai3 heteromeric channel

A general cellular response following depletion of intracellular calcium stores involves activation of store-operated channels (SOCs). While Orai1 forms the native Ca(2+) release-activated Ca(2+) (CRAC) channel in mast and T cells, the molecular architecture of less Ca(2+) selective SOCs is insuffic...

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Detalhes bibliográficos
Main Authors: Schindl, Rainer, Frischauf, Irene, Bergsmann, Judith, Muik, Martin, Derler, Isabella, Lackner, Barbara, Groschner, Klaus, Romanin, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780800/
https://ncbi.nlm.nih.gov/pubmed/19887627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907714106
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