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Cholesterol modulates Orai1 channel function
STIM1 (stromal interaction molecule 1) and Orai proteins are the essential components of Ca(2+) release–activated Ca(2+) (CRAC) channels. We focused on the role of cholesterol in the regulation of STIM1-mediated Orai1 currents. Chemically induced cholesterol depletion enhanced store-operated Ca(2+)...
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| Publicado no: | Sci Signal |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5373433/ https://ncbi.nlm.nih.gov/pubmed/26814231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aad7808 |
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