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IgG Fc engineering to modulate antibody effector functions
Therapeutic monoclonal antibodies are among the most effective biotherapeutics to date. An important aspect of antibodies is their ability to bind antigen while at the same time recruit immune effector functions. The majority of approved recombinant monoclonal antibody therapies are of the human IgG...
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| Veröffentlicht in: | Protein Cell |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Higher Education Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5777978/ https://ncbi.nlm.nih.gov/pubmed/28986820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-017-0473-8 |
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