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IgG Fc engineering to modulate antibody effector functions

Therapeutic monoclonal antibodies are among the most effective biotherapeutics to date. An important aspect of antibodies is their ability to bind antigen while at the same time recruit immune effector functions. The majority of approved recombinant monoclonal antibody therapies are of the human IgG...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Protein Cell
Main Authors: Wang, Xinhua, Mathieu, Mary, Brezski, Randall J.
Format: Artigo
Jezik:Inglês
Izdano: Higher Education Press 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777978/
https://ncbi.nlm.nih.gov/pubmed/28986820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-017-0473-8
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