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IgG Fc engineering to modulate antibody effector functions

Therapeutic monoclonal antibodies are among the most effective biotherapeutics to date. An important aspect of antibodies is their ability to bind antigen while at the same time recruit immune effector functions. The majority of approved recombinant monoclonal antibody therapies are of the human IgG...

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Detalhes bibliográficos
Publicado no:Protein Cell
Main Authors: Wang, Xinhua, Mathieu, Mary, Brezski, Randall J.
Formato: Artigo
Idioma:Inglês
Publicado em: Higher Education Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777978/
https://ncbi.nlm.nih.gov/pubmed/28986820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-017-0473-8
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