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A convergent, scalable and stereoselective synthesis of azole CYP51 inhibitors

The study and development of azole-based CYP51 inhibitors is an active area of research across disciplines of biochemistry, pharmacology and infectious disease. Support of in vitro and in vivo studies require the development of robust asymmetric routes to single enantiomer products of this class of...

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Dettagli Bibliografici
Pubblicato in:Tetrahedron Lett
Autori principali: Lepesheva, Galina, Christov, Plamen, Sulikowski, Gary A., Kim, Kwangho
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777588/
https://ncbi.nlm.nih.gov/pubmed/29371747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2017.09.070
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