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A convergent, scalable and stereoselective synthesis of azole CYP51 inhibitors

The study and development of azole-based CYP51 inhibitors is an active area of research across disciplines of biochemistry, pharmacology and infectious disease. Support of in vitro and in vivo studies require the development of robust asymmetric routes to single enantiomer products of this class of...

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Detalhes bibliográficos
Publicado no:Tetrahedron Lett
Main Authors: Lepesheva, Galina, Christov, Plamen, Sulikowski, Gary A., Kim, Kwangho
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777588/
https://ncbi.nlm.nih.gov/pubmed/29371747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2017.09.070
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