Population pharmacodynamic modelling of midazolam induced sedation in terminally ill adult patients

AIMS: Midazolam is the drug of choice for palliative sedation and is titrated to achieve the desired level of sedation. A previous pharmacokinetic (PK) study showed that variability between patients could be partly explained by renal function and inflammatory status. The goal of this study was to co...

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Detaylı Bibliyografya
Yayımlandı:Br J Clin Pharmacol
Asıl Yazarlar: Franken, Linda G., de Winter, Brenda C. M., Masman, Anniek D., van Dijk, Monique, Baar, Frans P. M., Tibboel, Dick, Koch, Birgit C. P., van Gelder, Teun, Mathot, Ron A. A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2017
Konular:
Therapeutics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777431/
https://ncbi.nlm.nih.gov/pubmed/28960387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13442
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