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Hypoalbuminaemia and decreased midazolam clearance in terminally ill adult patients, an inflammatory effect?

AIMS: Midazolam is the drug of choice for palliative sedation and is titrated to achieve the desired level of sedation. Because of large inter‐individual variability (IIV), however, the time it takes to achieve adequate sedation varies widely. It would therefore greatly improve clinical care if an i...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Br J Clin Pharmacol
Päätekijät: Franken, Linda G., Masman, Anniek D., de Winter, Brenda C. M., Baar, Frans P. M., Tibboel, Dick, van Gelder, Teun, Koch, Birgit C. P., Mathot, Ron A. A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510071/
https://ncbi.nlm.nih.gov/pubmed/28177137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13259
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