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Pharmacokinetics of Morphine, Morphine-3-Glucuronide and Morphine-6-Glucuronide in Terminally Ill Adult Patients

BACKGROUND AND OBJECTIVE: Morphine dosing can be challenging in terminally ill adult patients due to the heterogeneous nature of the population and the difficulty of accurately assessing pain during sedation. To determine the pharmacokinetics of morphine, morphine-3-glucuronide (M3G) and morphine-6-...

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Publicado no:Clin Pharmacokinet
Main Authors: Franken, Linda G., Masman, Anniek D., de Winter, Brenda C. M., Koch, Birgit C. P., Baar, Frans P. M., Tibboel, Dick, van Gelder, Teun, Mathot, Ron A. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875954/
https://ncbi.nlm.nih.gov/pubmed/26715216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-015-0345-4
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