Pharmacokinetic role of protein binding of mycophenolic acid and its glucuronide metabolite in renal transplant recipients

Mycophenolic acid (MPA), the active compound of mycophenolate mofetil (MMF), is used to prevent graft rejection in renal transplant recipients. MPA is glucuronidated to the metabolite MPAG, which exhibits enterohepatic recirculation (EHC). MPA binds for 97% and MPAG binds for 82% to plasma proteins....

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: de Winter, Brenda C. M., van Gelder, Teun, Sombogaard, Ferdi, Shaw, Leslie M., van Hest, Reinier M., Mathot, Ron A. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2009
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784070/
https://ncbi.nlm.nih.gov/pubmed/19904584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-009-9136-6
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky