Time-dependent clearance of mycophenolic acid in renal transplant recipients

AIMS: Pharmacokinetic studies of the immunosuppressive compound mycophenolic acid (MPA) have shown a structural decrease in clearance (CL) over time after renal transplantation. The aim of this study was to characterize the time-dependent CL of MPA by means of a population pharmacokinetic meta-analy...

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Detalhes bibliográficos
Main Authors: van Hest, Reinier M, van Gelder, Teun, Bouw, René, Goggin, Timothy, Gordon, Robert, Mamelok, Richard D, Mathot, Ron A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
Assuntos:
Pharmacokinetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000600/
https://ncbi.nlm.nih.gov/pubmed/17214827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2006.02841.x
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