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Pharmacokinetics of Morphine, Morphine-3-Glucuronide and Morphine-6-Glucuronide in Terminally Ill Adult Patients

BACKGROUND AND OBJECTIVE: Morphine dosing can be challenging in terminally ill adult patients due to the heterogeneous nature of the population and the difficulty of accurately assessing pain during sedation. To determine the pharmacokinetics of morphine, morphine-3-glucuronide (M3G) and morphine-6-...

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Vydáno v:Clin Pharmacokinet
Hlavní autoři: Franken, Linda G., Masman, Anniek D., de Winter, Brenda C. M., Koch, Birgit C. P., Baar, Frans P. M., Tibboel, Dick, van Gelder, Teun, Mathot, Ron A. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875954/
https://ncbi.nlm.nih.gov/pubmed/26715216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-015-0345-4
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