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Phosphorylation of the E3 ubiquitin protein ligase ITCH diminishes binding to its cognate E2 ubiquitin ligase

Heightened and extended inflammation underlies the pathogenesis of many disorders, including inflammatory bowel disease, sepsis, and inflammatory arthritis. Ubiquitin networks help dictate the strength and duration of inflammatory signaling. In innate immunity, the itchy E3 ubiquitin protein ligase...

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Podrobná bibliografie
Vydáno v:J Biol Chem
Hlavní autoři: Perez, Jessica M., Chen, Yinghua, Xiao, Tsan S., Abbott, Derek W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777250/
https://ncbi.nlm.nih.gov/pubmed/29212706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000408
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