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Regulation of autoimmune disease by the E3 ubiquitin ligase Itch
Itch is a HECT type E3 ubiquitin ligase that is required to prevent the development of autoimmune disease in both mice and humans. Itch is expressed in most mammalian cell types, and, based on published data, it regulates many cellular pathways ranging from T cell differentiation to liver tumorigene...
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| Publié dans: | Cell Immunol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6935763/ https://ncbi.nlm.nih.gov/pubmed/31126634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2019.04.004 |
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