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Regulation of autoimmune disease by the E3 ubiquitin ligase Itch

Itch is a HECT type E3 ubiquitin ligase that is required to prevent the development of autoimmune disease in both mice and humans. Itch is expressed in most mammalian cell types, and, based on published data, it regulates many cellular pathways ranging from T cell differentiation to liver tumorigene...

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Detalhes bibliográficos
Publicado no:Cell Immunol
Main Authors: Moser, Emily K., Oliver, Paula M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6935763/
https://ncbi.nlm.nih.gov/pubmed/31126634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2019.04.004
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