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The E3 ubiquitin ligase Itch is required for the differentiation of follicular helper T cells

Follicular helper T cells (T(FH) cells) are responsible for effective B cell–mediated immunity, and Bcl-6 is a central factor for the differentiation of T(FH) cells. However, the molecular mechanisms that regulate the induction of T(FH) cells remain unclear. Here we found that the E3 ubiquitin ligas...

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Bibliografske podrobnosti
izdano v:Nat Immunol
Main Authors: Xiao, Nengming, Eto, Danelle, Elly, Chris, Peng, Guiying, Crotty, Shane, Liu, Yun-Cai
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289613/
https://ncbi.nlm.nih.gov/pubmed/24859451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2912
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