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Bcl6 dependent T follicular helper cell differentiation diverges from effector cell differentiation during priming and depends on the gene Icos

The nature of follicular helper CD4(+) T (Tfh) cell differentiation remains controversial, including the minimal signals required for Tfh differentiation, and the time at which Tfh differentiation occurs. Here we determine that Tfh development initiates immediately during dendritic cell (DC) priming...

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Detalhes bibliográficos
Main Authors: Choi, Youn Soo, Kageyama, Robin, Eto, Danelle, Escobar, Tania C., Johnston, Robert J., Monticelli, Laurel, Lao, Christopher, Crotty, Shane
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124577/
https://ncbi.nlm.nih.gov/pubmed/21636296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.03.023
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