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Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation

Effective B cell–mediated immunity and antibody responses often require help from CD4(+) T cells. It is thought that a distinct CD4(+) effector T cell subset, called T follicular helper cells (T(FH)), provides this help; however, the molecular requirements for T(FH) differentiation are unknown. We f...

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Bibliografische gegevens
Hoofdauteurs: Johnston, Robert J., Poholek, Amanda C., DiToro, Daniel, Yusuf, Isharat, Eto, Danelle, Barnett, Burton, Dent, Alexander L., Craft, Joe, Crotty, Shane
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766560/
https://ncbi.nlm.nih.gov/pubmed/19608860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1175870
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