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The E3 ubiquitin ligase Itch is required for the differentiation of follicular helper T cells
Follicular helper T cells (T(FH) cells) are responsible for effective B cell–mediated immunity, and Bcl-6 is a central factor for the differentiation of T(FH) cells. However, the molecular mechanisms that regulate the induction of T(FH) cells remain unclear. Here we found that the E3 ubiquitin ligas...
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| Опубликовано в: : | Nat Immunol |
|---|---|
| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4289613/ https://ncbi.nlm.nih.gov/pubmed/24859451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2912 |
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