Genomic landscape of atypical adenomatous hyperplasia reveals divergent modes to lung adenocarcinoma

There is a dearth of knowledge about the pathogenesis of premalignant lung lesions, especially for atypical adenomatous hyperplasia (AAH), the only known precursor for the major lung cancer subtype adenocarcinoma (LUAD). In this study, we performed deep DNA and RNA sequencing analyses of a set of AA...

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Publicado en:Cancer Res
Autores principales: Sivakumar, Smruthy, Anthony San Lucas, F., McDowell, Tina L., Lang, Wenhua, Xu, Li, Fujimoto, Junya, Zhang, Jianjun, Futreal, P. Andrew, Fukuoka, Junya, Yatabe, Yasushi, Dubinett, Steven M., Spira, Avrum E., Fowler, Jerry, Hawk, Ernest T., Wistuba, Ignacio I., Scheet, Paul, Kadara, Humam
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774855/
https://ncbi.nlm.nih.gov/pubmed/28951454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-1605
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