Driver Mutations in Normal Airway Epithelium Elucidate Spatiotemporal Resolution of Lung Cancer

Rationale: Uninvolved normal-appearing airway epithelium has been shown to exhibit specific mutations characteristic of nearby non–small cell lung cancers (NSCLCs). Yet, its somatic mutational landscape in patients with early-stage NSCLC is unknown. Objectives: To comprehensively survey the somatic...

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Vydáno v:Am J Respir Crit Care Med
Hlavní autoři: Kadara, Humam, Sivakumar, Smruthy, Jakubek, Yasminka, San Lucas, F. Anthony, Lang, Wenhua, McDowell, Tina, Weber, Zachary, Behrens, Carmen, Davies, Gareth E., Kalhor, Neda, Moran, Cesar, El-Zein, Randa, Mehran, Reza, Swisher, Stephen G., Wang, Jing, Zhang, Jianjun, Fujimoto, Junya, Fowler, Jerry, Heymach, John V., Dubinett, Steven, Spira, Avrum E., Ehli, Erik A., Wistuba, Ignacio I., Scheet, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2019
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775870/
https://ncbi.nlm.nih.gov/pubmed/30896962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201806-1178OC
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