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Genome-Wide Gene Expression Changes in the Normal-Appearing Airway during the Evolution of Smoking-Associated Lung Adenocarcinoma

Smoking perpetuates in cytologically normal airways a molecular “field of injury” that is pertinent to lung cancer and early detection. The evolution of airway field changes prior to lung oncogenesis is poorly understood largely due to the long latency of lung cancer in smokers. Here, we studied air...

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Détails bibliographiques
Publié dans:Cancer Prev Res (Phila)
Auteurs principaux: Kantrowitz, Jacob, Sinjab, Ansam, Xu, Li, McDowell, Tina L., Sivakumar, Smruthy, Lang, Wenhua, Nunomura-Nakamura, Sayuri, Fukuoka, Junya, Nemer, Georges, Darwiche, Nadine, Chami, Hassan, Tfayli, Arafat, Wistuba, Ignacio I., Scheet, Paul, Fujimoto, Junya, Spira, Avrum E., Kadara, Humam
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679600/
https://ncbi.nlm.nih.gov/pubmed/29382653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-17-0295
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