Transcriptomic Alterations in Lung Adenocarcinoma Unveil New Mechanisms Targeted by the TBX2 Subfamily of Tumor Suppressor Genes

T-box (TBX) transcription factors are evolutionary conserved genes and master transcriptional regulators. In mammals, TBX2 subfamily (TBX2, TBX3, TBX4, and TBX5) genes are expressed in the developing lung bud and tracheae. Our group previously showed that the expression of TBX2 subfamily was signifi...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Khalil, Athar, Dekmak, Batoul, Boulos, Fouad, Kantrowitz, Jake, Spira, Avrum, Fujimoto, Junya, Kadara, Humam, El-Hachem, Nehme, Nemer, Georges
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6218583/
https://ncbi.nlm.nih.gov/pubmed/30425966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00482
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