Transcriptomic Alterations in Lung Adenocarcinoma Unveil New Mechanisms Targeted by the TBX2 Subfamily of Tumor Suppressor Genes

T-box (TBX) transcription factors are evolutionary conserved genes and master transcriptional regulators. In mammals, TBX2 subfamily (TBX2, TBX3, TBX4, and TBX5) genes are expressed in the developing lung bud and tracheae. Our group previously showed that the expression of TBX2 subfamily was signifi...

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Vydáno v:Front Oncol
Hlavní autoři: Khalil, Athar, Dekmak, Batoul, Boulos, Fouad, Kantrowitz, Jake, Spira, Avrum, Fujimoto, Junya, Kadara, Humam, El-Hachem, Nehme, Nemer, Georges
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6218583/
https://ncbi.nlm.nih.gov/pubmed/30425966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00482
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