Genomic landscape of atypical adenomatous hyperplasia reveals divergent modes to lung adenocarcinoma

There is a dearth of knowledge about the pathogenesis of premalignant lung lesions, especially for atypical adenomatous hyperplasia (AAH), the only known precursor for the major lung cancer subtype adenocarcinoma (LUAD). In this study, we performed deep DNA and RNA sequencing analyses of a set of AA...

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Gepubliceerd in:Cancer Res
Hoofdauteurs: Sivakumar, Smruthy, Anthony San Lucas, F., McDowell, Tina L., Lang, Wenhua, Xu, Li, Fujimoto, Junya, Zhang, Jianjun, Futreal, P. Andrew, Fukuoka, Junya, Yatabe, Yasushi, Dubinett, Steven M., Spira, Avrum E., Fowler, Jerry, Hawk, Ernest T., Wistuba, Ignacio I., Scheet, Paul, Kadara, Humam
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774855/
https://ncbi.nlm.nih.gov/pubmed/28951454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-1605
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