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Genomic landscape of atypical adenomatous hyperplasia reveals divergent modes to lung adenocarcinoma

There is a dearth of knowledge about the pathogenesis of premalignant lung lesions, especially for atypical adenomatous hyperplasia (AAH), the only known precursor for the major lung cancer subtype adenocarcinoma (LUAD). In this study, we performed deep DNA and RNA sequencing analyses of a set of AA...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Sivakumar, Smruthy, Anthony San Lucas, F., McDowell, Tina L., Lang, Wenhua, Xu, Li, Fujimoto, Junya, Zhang, Jianjun, Futreal, P. Andrew, Fukuoka, Junya, Yatabe, Yasushi, Dubinett, Steven M., Spira, Avrum E., Fowler, Jerry, Hawk, Ernest T., Wistuba, Ignacio I., Scheet, Paul, Kadara, Humam
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774855/
https://ncbi.nlm.nih.gov/pubmed/28951454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-1605
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