Genomic landscape of allelic imbalance in premalignant atypical adenomatous hyperplasias of the lung

BACKGROUND: Genomic investigation of atypical adenomatous hyperplasia (AAH), the only known precursor lesion to lung adenocarcinomas (LUAD), presents challenges due to the low mutant cell fractions. This necessitates sensitive methods for detection of chromosomal aberrations to better study the role...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Sivakumar, Smruthy, San Lucas, F. Anthony, Jakubek, Yasminka A., McDowell, Tina L., Lang, Wenhua, Kallsen, Noah, Peyton, Shanna, Davies, Gareth E., Fukuoka, Junya, Yatabe, Yasushi, Zhang, Jianjun, Futreal, P. Andrew, Fowler, Jerry, Fujimoto, Junya, Ehli, Erik A., Hawk, Ernest T., Wistuba, Ignacio I., Kadara, Humam, Scheet, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491940/
https://ncbi.nlm.nih.gov/pubmed/30905849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.03.020
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