Genomic landscape of allelic imbalance in premalignant atypical adenomatous hyperplasias of the lung

BACKGROUND: Genomic investigation of atypical adenomatous hyperplasia (AAH), the only known precursor lesion to lung adenocarcinomas (LUAD), presents challenges due to the low mutant cell fractions. This necessitates sensitive methods for detection of chromosomal aberrations to better study the role...

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Bibliografski detalji
Izdano u:EBioMedicine
Glavni autori: Sivakumar, Smruthy, San Lucas, F. Anthony, Jakubek, Yasminka A., McDowell, Tina L., Lang, Wenhua, Kallsen, Noah, Peyton, Shanna, Davies, Gareth E., Fukuoka, Junya, Yatabe, Yasushi, Zhang, Jianjun, Futreal, P. Andrew, Fowler, Jerry, Fujimoto, Junya, Ehli, Erik A., Hawk, Ernest T., Wistuba, Ignacio I., Kadara, Humam, Scheet, Paul
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2019
Teme:
Research paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491940/
https://ncbi.nlm.nih.gov/pubmed/30905849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.03.020
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