Genomic landscape of allelic imbalance in premalignant atypical adenomatous hyperplasias of the lung

BACKGROUND: Genomic investigation of atypical adenomatous hyperplasia (AAH), the only known precursor lesion to lung adenocarcinomas (LUAD), presents challenges due to the low mutant cell fractions. This necessitates sensitive methods for detection of chromosomal aberrations to better study the role...

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Enregistré dans:
Détails bibliographiques
Publié dans:EBioMedicine
Auteurs principaux: Sivakumar, Smruthy, San Lucas, F. Anthony, Jakubek, Yasminka A., McDowell, Tina L., Lang, Wenhua, Kallsen, Noah, Peyton, Shanna, Davies, Gareth E., Fukuoka, Junya, Yatabe, Yasushi, Zhang, Jianjun, Futreal, P. Andrew, Fowler, Jerry, Fujimoto, Junya, Ehli, Erik A., Hawk, Ernest T., Wistuba, Ignacio I., Kadara, Humam, Scheet, Paul
Format: Artigo
Langue:Inglês
Publié: Elsevier 2019
Sujets:
Research paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491940/
https://ncbi.nlm.nih.gov/pubmed/30905849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.03.020
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