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Pan cancer patterns of allelic imbalance from chromosomal alterations in 33 tumor types
Somatic copy number alterations (SCNAs) serve as hallmarks of tumorigenesis and often result in deviations from one-to-one allelic ratios at heterozygous loci, leading to allelic imbalance (AI). The Cancer Genome Atlas (TCGA) reports SCNAs identified using a circular binary segmentation algorithm, p...
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| Publicado no: | Genetics |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8045738/ https://ncbi.nlm.nih.gov/pubmed/33683368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/genetics/iyaa021 |
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