Pan cancer patterns of allelic imbalance from chromosomal alterations in 33 tumor types

Somatic copy number alterations (SCNAs) serve as hallmarks of tumorigenesis and often result in deviations from one-to-one allelic ratios at heterozygous loci, leading to allelic imbalance (AI). The Cancer Genome Atlas (TCGA) reports SCNAs identified using a circular binary segmentation algorithm, p...

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Bibliografische gegevens
Gepubliceerd in:Genetics
Hoofdauteurs: Sivakumar, Smruthy, San Lucas, F Anthony, Jakubek, Yasminka A, Ozcan, Zuhal, Fowler, Jerry, Scheet, Paul
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2021
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Investigation
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8045738/
https://ncbi.nlm.nih.gov/pubmed/33683368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/genetics/iyaa021
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