Genomic Landscape Established by Allelic Imbalance in the Cancerization Field of a Normal Appearing Airway

Visually normal cells adjacent to, and extending from, tumors of the lung may carry molecular alterations characteristics of the tumor itself, an effect referred to as airway field of cancerization. This airway field has been postulated as a model for early events in lung cancer pathogenesis. Yet th...

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Publié dans:Cancer Res
Auteurs principaux: Jakubek, Yasminka, Lang, Wenhua, Vattathil, Selina, Garcia, Melinda, Xu, Li, Huang, Lili, Yoo, Suk-Young, Shen, Li, Lu, Wei, Chow, Chi-Wan, Weber, Zachary, Davies, Gareth, Huang, Jing, Behrens, Carmen, Kalhor, Neda, Moran, Cesar, Fujimoto, Junya, Mehran, Reza, El-Zein, Randa, Swisher, Stephen G., Wang, Jing, Fowler, Jerry, Spira, Avrum E., Ehli, Erik A., Wistuba, Ignacio I., Scheet, Paul, Kadara, Humam
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393446/
https://ncbi.nlm.nih.gov/pubmed/27216194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-3064
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