Wird geladen...

Identification of Allelic Imbalance with a Statistical Model for Subtle Genomic Mosaicism

Genetic heterogeneity in a mixed sample of tumor and normal DNA can confound characterization of the tumor genome. Numerous computational methods have been proposed to detect aberrations in DNA samples from tumor and normal tissue mixtures. Most of these require tumor purities to be at least 10–15%....

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Xia, Rui, Vattathil, Selina, Scheet, Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148184/
https://ncbi.nlm.nih.gov/pubmed/25166618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003765
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!