Development of Kras mutant lung adenocarcinoma in mice with knockout of the airway lineage-specific gene Gprc5a

Despite the urgency for prevention and treatment of lung adenocarcinoma (LUAD), we still do not know drivers in pathogenesis of the disease. Earlier work revealed that mice with knockout of the G-protein coupled receptor Gprc5a develop late onset lung tumors including LUADs. Here, we sought to furth...

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Publicat a:Int J Cancer
Autors principals: Fujimoto, Junya, Nunomura-Nakamura, Sayuri, Liu, Yihua, Lang, Wenhua, McDowell, Tina, Jakubek, Yasminka, Ezzeddine, Dalia, Ochieng, Joshua Kapere, Petersen, Jason, Davies, Gareth, Fukuoka, Junya, Wistuba, Ignacio I., Ehli, Erik, Fowler, Jerry, Scheet, Paul, Kadara, Humam
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774849/
https://ncbi.nlm.nih.gov/pubmed/28653505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.30851
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